YU142670

Modify Date: 2024-04-09 01:13:29

YU142670 Structure
YU142670 structure
Common Name YU142670
CAS Number 133847-06-0 Molecular Weight 203.224
Density 1.7±0.1 g/cm3 Boiling Point N/A
Molecular Formula C8H5N5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of YU142670


YU142670 is a highly specific, soluble OCRL/INPP5B inhibitor that directly interacts with the catalytic domain of INPP5B; induces enhanced actin polymerization and ruffle activity at the plasma membrane, increases the levels of PI(4,5)P2 in mouse embryonic fibroblasts or human dermal fibroblasts and inhibits the activity of over-expressed human OCRL in Cos-7 cells.

 Names

Name YU142670
Synonym More Synonyms

 YU142670 Biological Activity

Description YU142670 is a highly specific, soluble OCRL/INPP5B inhibitor that directly interacts with the catalytic domain of INPP5B; induces enhanced actin polymerization and ruffle activity at the plasma membrane, increases the levels of PI(4,5)P2 in mouse embryonic fibroblasts or human dermal fibroblasts and inhibits the activity of over-expressed human OCRL in Cos-7 cells.
References References 1. Pirruccello M, et al. ACS Chem Biol. 2014 Jun 20;9(6):1359-68. View Related Products by Target Protein Phosphatase/PTP

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Molecular Formula C8H5N5S
Molecular Weight 203.224
Exact Mass 203.026566
LogP 1.20
Index of Refraction 1.898

 Synonyms

YU142670
3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole
3-(4-Pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
MFCD06590438
1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 3-(4-pyridinyl)-
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