2089389-15-9

2089389-15-9 structure

Name: (R)-ZINC 3573
Chemical Name: (R)-ZINC-3573
CAS Number: 2089389-15-9
Molecular Formula: C₁₈H₂₁N₅
Molecular Weight: 307.393
Catalog: Research Areas Infection
Create Date: 2020-01-11 21:12:01
Modify Date: 2024-01-07 23:06:39
(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases; activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.

Name	(R)-ZINC-3573
Synonyms	(R)-ZINC-3573 3-Pyrrolidinamine, N,N-dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-, (3R)- (3R)-N,N-Dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3-pyrrolidinamine (R)-ZINC72453573 (R)-N,N-Dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3-pyrrolidinamine

Description	(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases; activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.
References	References 1. Lansu K, et al. Nat Chem Biol. 2017 May;13(5):529-536. View Related Products by Target Other Targets