1149750-69-5
1149750-69-5 structure
- Name: MK-3901
- Chemical Name: MK-3901
- CAS Number: 1149750-69-5
- Molecular Formula: C28H24FN5O2
- Molecular Weight: 481.531
- Create Date: 2020-01-11 15:12:50
- Modify Date: 2024-07-09 12:27:03
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MK-3901 is a potent, selective, orally active P2X3 antagonist with IC50 of 21 nM; demonstrates efficacy similar to that of naproxen, after 60 mg/kg (p.o.) administration with EC90 of approximately 3 uM in the rat CFA model of inflammatory pain.
| Name | MK-3901 |
|---|
| Description | MK-3901 is a potent, selective, orally active P2X3 antagonist with IC50 of 21 nM; demonstrates efficacy similar to that of naproxen, after 60 mg/kg (p.o.) administration with EC90 of approximately 3 uM in the rat CFA model of inflammatory pain. |
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| References | References 1. Ginnetti AT, et al. Bioorg Med Chem Lett. 2018 May 1;28(8):1392-1396. View Related Products by Target P2X Receptor |
| Molecular Formula | C28H24FN5O2 |
|---|---|
| Molecular Weight | 481.531 |