Name | BR103 |
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Description | BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM; displays high selectivity for C3aR over C5aR; induces paw oedema and mast cell activation in vivo in rats. |
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References | References 1. Lohman RJ, et al. Nat Commun. 2017 Aug 24;8(1):351. View Related Products by Target Complement System |
Molecular Formula | C24H28N6O3 |
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Molecular Weight | 448.527 |