1778655-51-8
1778655-51-8 structure
- Name: FT-001
- Chemical Name: FT-001
- CAS Number: 1778655-51-8
- Molecular Formula: C25H29N3O4S
- Molecular Weight: 467.584
- Create Date: 2020-01-11 20:25:49
- Modify Date: 2024-01-11 10:29:58
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FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1; inhibits the expression of MYC in the MV-4-11 cell line with IC50 of 0.46 uM, shows anti-proliferative activity with IC50 of 0.22 uM; displays complete tumor growth inhibition in mouse MV-4-11 xenograft model.
| Name | FT-001 |
|---|
| Description | FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1; inhibits the expression of MYC in the MV-4-11 cell line with IC50 of 0.46 uM, shows anti-proliferative activity with IC50 of 0.22 uM; displays complete tumor growth inhibition in mouse MV-4-11 xenograft model. |
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| References | References 1. Millan DS, et al. ACS Med Chem Lett. 2017 Jul 14;8(8):847-852. View Related Products by Target Bromodomain |
| Molecular Formula | C25H29N3O4S |
|---|---|
| Molecular Weight | 467.584 |