1961272-45-6

1961272-45-6 structure

Name: 6-MOMIPP
Chemical Name: 6-MOMIPP
CAS Number: 1961272-45-6
Molecular Formula: C₁₈H₁₆N₂O₂
Molecular Weight: 292.338
Create Date: 2020-01-11 15:09:50
Modify Date: 2024-01-14 18:41:15
6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro; demonstrates broad activity against the viability of multiple glioblastoma, melanoma and lung carcinoma cell lines; effectively inhibits growth of subcutaneous and intracerebral tumors without causing general toxicity in mice bearing human U251 glioblastoma xenografts .

Name	6-MOMIPP

Description	6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro; demonstrates broad activity against the viability of multiple glioblastoma, melanoma and lung carcinoma cell lines; effectively inhibits growth of subcutaneous and intracerebral tumors without causing general toxicity in mice bearing human U251 glioblastoma xenografts .
References	References 1. Du S, et al. Cancer Chemother Pharmacol. 2018 Nov 13. doi: 10.1007/s00280-018-3726-1. View Related Products by Target Microtubule/Tubulin

Molecular Formula	C₁₈H₁₆N₂O₂
Molecular Weight	292.338