- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: JNJ-40413269
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: JNJ-40413269
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- DC Chemicals Limited
- China
- Product Name: JNJ-40413269
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
1184847-16-2
1184847-16-2 structure
- Name: JNJ-40413269
- Chemical Name: JNJ-40413269
- CAS Number: 1184847-16-2
- Molecular Formula: C19H15ClF3N3O
- Molecular Weight: 393.794
- Create Date: 2020-01-12 13:57:51
- Modify Date: 2024-04-09 17:50:35
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JNJ-40413269 is a potent, selective, blood brain barrier (BBB) penetrant FAAH inhibitor with IC50 of 5.3 and 6.3 nM for hFAAH and rFAAH, respectively; exhibits a robust dose-dependent decrease in mechanical allodynia in the spinal nerve ligation model of neuropathic pain; strongly raises the brain levels of AEA, PEA and OEA.
| Name | JNJ-40413269 |
|---|
| Description | JNJ-40413269 is a potent, selective, blood brain barrier (BBB) penetrant FAAH inhibitor with IC50 of 5.3 and 6.3 nM for hFAAH and rFAAH, respectively; exhibits a robust dose-dependent decrease in mechanical allodynia in the spinal nerve ligation model of neuropathic pain; strongly raises the brain levels of AEA, PEA and OEA. |
|---|---|
| References | References 1. Keith JM, et al. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1280-4. View Related Products by Target FAAH |
| Molecular Formula | C19H15ClF3N3O |
|---|---|
| Molecular Weight | 393.794 |