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1242328-82-0

1242328-82-0 structure
1242328-82-0 structure
  • Name: DS-6930
  • Chemical Name: DS-6930
  • CAS Number: 1242328-82-0
  • Molecular Formula: C23H21N3O4
  • Molecular Weight: 403.438
  • Create Date: 2020-01-20 13:01:55
  • Modify Date: 2024-01-13 16:18:54
  • DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity. Diabetes Discontinued

Name DS-6930
Description DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity. Diabetes Discontinued
References References 1. Shinozuka T, et al. Bioorg Med Chem. 2018 Oct 1;26(18):5099-5117. 2. Shinozuka T, et al. Bioorg Med Chem. 2018 Oct 1;26(18):5079-5098. View Related Products by Target PPAR Diabetes
Molecular Formula C23H21N3O4
Molecular Weight 403.438