1599460-95-3
1599460-95-3 structure
- Name: CFI-401870
- Chemical Name: CFI-401870
- CAS Number: 1599460-95-3
- Molecular Formula: C30H31N5O2
- Molecular Weight: 493.611
- Create Date: 2020-01-11 19:41:50
- Modify Date: 2023-10-05 18:22:40
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A potent, selective, orally active Mps1 (TTK) inhibitor with IC50 of 3.1 nM; displays low off-target activity (>500-fold) and microsomal stability; inhibits HCT116 cell growth with GI50 of <0.1 uM, demonstrates in vivo tumor growth inhibition.
| Name | CFI-401870 |
|---|
| Description | A potent, selective, orally active Mps1 (TTK) inhibitor with IC50 of 3.1 nM; displays low off-target activity (>500-fold) and microsomal stability; inhibits HCT116 cell growth with GI50 of <0.1 uM, demonstrates in vivo tumor growth inhibition. |
|---|---|
| References | References 1. Liu Y, et al. J Med Chem. 2015 Apr 23;58(8):3366-92. View Related Products by Target Monopolar Spindle 1 (Mps1/TTK) |
| Molecular Formula | C30H31N5O2 |
|---|---|
| Molecular Weight | 493.611 |