1630760-58-5

1630760-58-5 structure

Name: ML379
Chemical Name: ML379
CAS Number: 1630760-58-5
Molecular Formula: C₁₅H₁₉N₃O₂
Molecular Weight: 273.33
Create Date: 2020-01-12 14:32:49
Modify Date: 2024-01-22 13:46:49
ML379 (CID71576758) is a potent, selective TP53 mutant cancer cells inhibitor with IC50 of 13 nM in sensitive HeLa cells (TP53 mutant); displays >1,000-fold selectivity over insensitive A549 cells (TP53 wild type); displays low nM activity in a larger panel of TP53 mutant cell lines.

Name	ML379

Description	ML379 (CID71576758) is a potent, selective TP53 mutant cancer cells inhibitor with IC50 of 13 nM in sensitive HeLa cells (TP53 mutant); displays >1,000-fold selectivity over insensitive A549 cells (TP53 wild type); displays low nM activity in a larger panel of TP53 mutant cell lines.
References	References 1. Lewis TA, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. View Related Products by Target MDM2-p53

Molecular Formula	C₁₅H₁₉N₃O₂
Molecular Weight	273.33