ML379

Modify Date: 2024-01-22 13:46:49

ML379 structure	Common Name	ML379
	CAS Number	1630760-58-5	Molecular Weight	273.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₉N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ML379

ML379 (CID71576758) is a potent, selective TP53 mutant cancer cells inhibitor with IC50 of 13 nM in sensitive HeLa cells (TP53 mutant); displays >1,000-fold selectivity over insensitive A549 cells (TP53 wild type); displays low nM activity in a larger panel of TP53 mutant cell lines.

Name	ML379

Description	ML379 (CID71576758) is a potent, selective TP53 mutant cancer cells inhibitor with IC50 of 13 nM in sensitive HeLa cells (TP53 mutant); displays >1,000-fold selectivity over insensitive A549 cells (TP53 wild type); displays low nM activity in a larger panel of TP53 mutant cell lines.
References	References 1. Lewis TA, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. View Related Products by Target MDM2-p53