1776931-05-5
1776931-05-5 structure
- Name: CBR-096-4
- Chemical Name: CBR-096-4
- CAS Number: 1776931-05-5
- Molecular Formula: C35H40N8O4
- Molecular Weight: 636.757
- Create Date: 2020-01-20 18:10:56
- Modify Date: 2024-04-11 11:11:19
-
A derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues; devoid of antifungal and human cytochrome P450 inhibitory activity with excellent pharmacokinetics, safety, and efficacy in rodent models of lung, liver, and skin fibrosis.
| Name | CBR-096-4 |
|---|
| Description | A derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues; devoid of antifungal and human cytochrome P450 inhibitory activity with excellent pharmacokinetics, safety, and efficacy in rodent models of lung, liver, and skin fibrosis. |
|---|---|
| References | References 1. Bollong MJ, et al. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4679-4684. View Related Products by Target Other Targets |
| Molecular Formula | C35H40N8O4 |
|---|---|
| Molecular Weight | 636.757 |