1853269-07-4
1853269-07-4 structure
- Name: LSD1 inhibitor 24
- Chemical Name: LSD1 inhibitor 24
- CAS Number: 1853269-07-4
- Molecular Formula: C26H25ClFN7O
- Molecular Weight: 505.982
- Create Date: 2020-01-15 16:13:14
- Modify Date: 2024-01-09 21:58:10
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LSD1 inhibitor 24 is a novel potent, selective lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 1 nM, induces CD11b expression in THP-1 cells with EC50 of 8 nM; demonstrates attenuating the hERG inhibition and improving oral bioavailability.
| Name | LSD1 inhibitor 24 |
|---|
| Description | LSD1 inhibitor 24 is a novel potent, selective lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 1 nM, induces CD11b expression in THP-1 cells with EC50 of 8 nM; demonstrates attenuating the hERG inhibition and improving oral bioavailability. |
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| References | References 1. Nie Z, et al. Bioorg Med Chem Lett. 2018 Nov 3. pii: S0960-894X(18)30855-2. View Related Products by Target Histone Demethylase |
| Molecular Formula | C26H25ClFN7O |
|---|---|
| Molecular Weight | 505.982 |