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2109450-40-8

2109450-40-8 structure
2109450-40-8 structure
  • Name: RN 9893 hydrochloride
  • Chemical Name: RN-9893 hydrochloride
  • CAS Number: 2109450-40-8
  • Molecular Formula: C21H23F3N4O5S.HCl
  • Molecular Weight: 536.95
  • Create Date: 2020-01-20 19:04:56
  • Modify Date: 2024-07-28 09:21:47
  • A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively; >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets.

Name RN-9893 hydrochloride
Description A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively; >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets.
References References 1. Wei ZL, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. View Related Products by Target TRP Channel
Molecular Formula C21H23F3N4O5S.HCl
Molecular Weight 536.95