2218484-75-2
2218484-75-2 structure
- Name: PF-06815189
- Chemical Name: PF-06815189
- CAS Number: 2218484-75-2
- Molecular Formula: C19H17F3N6O2
- Molecular Weight: 418.38
- Create Date: 2020-01-19 20:02:02
- Modify Date: 2024-06-06 18:43:36
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PF-06815189 is a potent, selective phosphodiesterase 2 (PDE2) inhibitor with IC50 of 0.4 nM, >1,000-fold selectivity over PDE5; also demonstrates no significant activities (EC50 >10 μM) in a broad spectrum BioPrint panel; possesses favorable pharmacological and in vitro ADME profile, the pharmacokinetic attributes.
| Name | PF-06815189 |
|---|
| Description | PF-06815189 is a potent, selective phosphodiesterase 2 (PDE2) inhibitor with IC50 of 0.4 nM, >1,000-fold selectivity over PDE5; also demonstrates no significant activities (EC50 >10 μM) in a broad spectrum BioPrint panel; possesses favorable pharmacological and in vitro ADME profile, the pharmacokinetic attributes. |
|---|---|
| References | References 1. Stepan AF, et al. ACS Med Chem Lett. 2018 Jan 4;9(2):68-72. View Related Products by Target Phosphodiesterase (PDE) |
| Molecular Formula | C19H17F3N6O2 |
|---|---|
| Molecular Weight | 418.38 |