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  • DC Chemicals Limited
  • China
  • Product Name: Z-590
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

433954-52-0

433954-52-0 structure
433954-52-0 structure
  • Name: Z-590
  • Chemical Name: Z-590
  • CAS Number: 433954-52-0
  • Molecular Formula: C21H16N2O3S
  • Molecular Weight: 376.43
  • Create Date: 2020-01-19 21:52:55
  • Modify Date: 2024-04-02 21:31:43
  • Z-590 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity; significantly decreases the production of nitric oxide (NO), TNF-α, interleukin (IL)-6, IL-1β, cyclooxygenase (COX-2), inducible nitric oxide synthase (iNOS) as well as reactive oxygen species (ROS) involved in inhibiting MAKPs signalling pathway in LPS-stimulated microglia cells; suppresses cartilage destruction in adjuvant-induced arthritis via inhibition of macrophage inflammatory activatio in vivo.

Name Z-590
Description Z-590 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity; significantly decreases the production of nitric oxide (NO), TNF-α, interleukin (IL)-6, IL-1β, cyclooxygenase (COX-2), inducible nitric oxide synthase (iNOS) as well as reactive oxygen species (ROS) involved in inhibiting MAKPs signalling pathway in LPS-stimulated microglia cells; suppresses cartilage destruction in adjuvant-induced arthritis via inhibition of macrophage inflammatory activatio in vivo.
References References 1. Zhang Z, et al. Immunopharmacol Immunotoxicol. 2018 Apr;40(2):149-157. 2. Zhang Y, et al. Clin Exp Pharmacol Physiol. 2016 Nov;43(11):1134-1144. View Related Products by Target Other Targets
Molecular Formula C21H16N2O3S
Molecular Weight 376.43