788146-30-5
788146-30-5 structure
- Name: AZ-2
- Chemical Name: AZ-2
- CAS Number: 788146-30-5
- Molecular Formula: C24H32ClN3O2
- Molecular Weight: 429.989
- Create Date: 2020-01-11 18:13:44
- Modify Date: 2024-01-06 09:47:32
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AZ-2 is a small molecule inducer of ABCA1 and apoE that act through indirect activation of the LXR pathway, shows purinergic receptor P2X7 antagonist activity; upregulates ABCA1 across multiple CNS cell types, including human astrocytes, pericytes, and microglia, through an indirect LXR mechanism and that also independently inhibit P2X7 receptor activity.
| Name | AZ-2 |
|---|
| Description | AZ-2 is a small molecule inducer of ABCA1 and apoE that act through indirect activation of the LXR pathway, shows purinergic receptor P2X7 antagonist activity; upregulates ABCA1 across multiple CNS cell types, including human astrocytes, pericytes, and microglia, through an indirect LXR mechanism and that also independently inhibit P2X7 receptor activity. |
|---|---|
| References | References 1. Fan J, et al. J Lipid Res. 2018 May;59(5):830-842. View Related Products by Target P2X Receptor |
| Molecular Formula | C24H32ClN3O2 |
|---|---|
| Molecular Weight | 429.989 |