2062663-63-0

2062663-63-0 structure
2062663-63-0 structure
  • Name: T-Boc-aminooxy-peg4-ch2co2-t-bu
  • Chemical Name: Boc-Aminooxy-PEG4-CH2-Boc
  • CAS Number: 2062663-63-0
  • Molecular Formula: C19H37NO9
  • Molecular Weight: 423.50
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-07 23:41:51
  • Modify Date: 2024-07-22 19:19:10
  • Boc-Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-Aminooxy-PEG4-CH2-Boc
Synonyms MFCD30536164
Description Boc-Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

Molecular Formula C19H37NO9
Molecular Weight 423.50