2388521-20-6

2388521-20-6 structure
2388521-20-6 structure
  • Name: Hydroxy-PEG12-t-butyl ester
  • Chemical Name: Hydroxy-PEG12-Boc
  • CAS Number: 2388521-20-6
  • Molecular Formula: C31H62O15
  • Molecular Weight: 674.81
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-11 20:13:15
  • Modify Date: 2024-01-11 00:16:59
  • Hydroxy-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Hydroxy-PEG12-Boc
Description Hydroxy-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C31H62O15
Molecular Weight 674.81