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1338824-20-6

1338824-20-6 structure
1338824-20-6 structure
  • Name: NCGC00229600
  • Chemical Name: NCGC00229600
  • CAS Number: 1338824-20-6
  • Molecular Formula: C30H29N3O3
  • Molecular Weight: 479.57
  • Catalog: Signaling Pathways GPCR/G Protein TSH Receptor
  • Create Date: 2020-04-08 18:28:18
  • Modify Date: 2024-01-17 11:53:51
  • NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease[1].

Name NCGC00229600
Description NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease[1].
Related Catalog
References

[1]. Neumann S, et al. A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor. J Clin Endocrinol Metab. 2011 Feb;96(2):548-54.

Molecular Formula C30H29N3O3
Molecular Weight 479.57