192132-77-7

192132-77-7 structure

192132-77-7 structure

Name: 2-(2-((tert-Butoxycarbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate
Chemical Name: Tos-PEG2-NH-Boc
CAS Number: 192132-77-7
Molecular Formula: C₁₆H₂₅NO₆S
Molecular Weight: 359.44
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-13 09:02:35
Modify Date: 2024-01-08 22:34:54
Tos-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Tos-PEG2-NH-Boc
Synonyms	MFCD28506265

Description	Tos-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₆H₂₅NO₆S
Molecular Weight	359.44