Shanghai Nianxing Industrial Co., Ltd
China
Product Name: APN-C3-NH-Boc
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: tert-butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1539292-60-8

1539292-60-8 structure

1539292-60-8 structure

Name: tert-butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate
Chemical Name: APN-C3-NH-Boc
CAS Number: 1539292-60-8
Molecular Formula: C₁₈H₂₁N₃O₃
Molecular Weight: 327.38
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:55:23
Modify Date: 2024-01-02 10:23:23
APN-C3-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	APN-C3-NH-Boc

Description	APN-C3-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₈H₂₁N₃O₃
Molecular Weight	327.38