2128735-28-2

2128735-28-2 structure
2128735-28-2 structure
  • Name: T-Boc-n-amido-peg5-ms
  • Chemical Name: Boc-N-Amido-PEG5-Ms
  • CAS Number: 2128735-28-2
  • Molecular Formula: C16H33NO9S
  • Molecular Weight: 415.50
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:48:46
  • Modify Date: 2024-01-30 12:31:52
  • Boc-N-Amido-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-N-Amido-PEG5-Ms
Synonyms MFCD31536757
Description Boc-N-Amido-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H33NO9S
Molecular Weight 415.50