2375611-66-6

2375611-66-6 structure

2375611-66-6 structure

Name: 1-Hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid
Chemical Name: Hydroxy-PEG10-acid
CAS Number: 2375611-66-6
Molecular Formula: C₂₃H₄₆O₁₃
Molecular Weight: 530.60
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 21:27:23
Modify Date: 2024-01-10 18:30:48
Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Hydroxy-PEG10-acid

Description	Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₂₃H₄₆O₁₃
Molecular Weight	530.60