2194563-84-1

2194563-84-1 structure

2194563-84-1 structure

Name: tert-Butyl (2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)carbamate
Chemical Name: Methyltetrazine-PEG4-NH-Boc
CAS Number: 2194563-84-1
Molecular Formula: C₂₂H₃₃N₅O₆
Molecular Weight: 463.53
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:47:59
Modify Date: 2024-02-01 18:46:19
Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methyltetrazine-PEG4-NH-Boc
Synonyms	MFCD31615440

Description	Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₂H₃₃N₅O₆
Molecular Weight	463.53