2353409-57-9

2353409-57-9 structure

Name: Di-tert-butyl 16-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioate
Chemical Name: N-(Amino-PEG3)-N-bis(PEG4-Boc)
CAS Number: 2353409-57-9
Molecular Formula: C₃₈H₇₆N₂O₁₅
Molecular Weight: 801.01
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:57:54
Modify Date: 2024-09-15 12:04:05
N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(Amino-PEG3)-N-bis(PEG4-Boc)

Description	N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₈H₇₆N₂O₁₅
Molecular Weight	801.01