2112731-48-1

2112731-48-1 structure
2112731-48-1 structure
  • Name: N-(Biotin-PEG4)-N-bis(PEG4-acid)
  • Chemical Name: N-(Biotin-PEG4)-N-bis(PEG4-acid)
  • CAS Number: 2112731-48-1
  • Molecular Formula: C42H78N4O18S
  • Molecular Weight: 959.15
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:13:06
  • Modify Date: 2024-01-09 07:46:31
  • N-(Biotin-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Biotin-PEG4)-N-bis(PEG4-acid)
Synonyms MFCD30723243
Description N-(Biotin-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C42H78N4O18S
Molecular Weight 959.15