2107273-62-9

2107273-62-9 structure

Name: N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3
Chemical Name: N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3
CAS Number: 2107273-62-9
Molecular Formula: C₄₅H₆₅ClN₂O₁₀
Molecular Weight: 829.46
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 17:23:40
Modify Date: 2024-01-09 15:37:14
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3

Description	N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₅H₆₅ClN₂O₁₀
Molecular Weight	829.46

Hazard Codes	Xi