2112737-74-1

2112737-74-1 structure
2112737-74-1 structure
  • Name: N-(Tos-peg4)-n-bis(peg4-t-butyl ester)
  • Chemical Name: N-(Tos-PEG4)-N-bis(PEG4-Boc)
  • CAS Number: 2112737-74-1
  • Molecular Formula: C45H81NO18S
  • Molecular Weight: 956.19
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:37:09
  • Modify Date: 2024-01-10 20:38:16
  • N-(Tos-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Tos-PEG4)-N-bis(PEG4-Boc)
Synonyms MFCD30828699
Description N-(Tos-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C45H81NO18S
Molecular Weight 956.19