Shanghai Nianxing Industrial Co., Ltd
China
Product Name: m-PEG12-2-methylacrylate
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Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

2867-46-1

2867-46-1 structure

2867-46-1 structure

Name: m-PEG12-2-methylacrylate
Chemical Name: Propargyl-PEG13-alcohol
CAS Number: 2867-46-1
Molecular Formula: C₂₉H₅₆O₁₄
Molecular Weight: 628.75
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 14:06:08
Modify Date: 2024-04-09 20:21:00
Propargyl-PEG13-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG13-alcohol

Description	Propargyl-PEG13-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₉H₅₆O₁₄
Molecular Weight	628.75