2169967-47-7

2169967-47-7 structure
2169967-47-7 structure
  • Name: mPEG16-Propyne
  • Chemical Name: Propargyl-PEG17-methane
  • CAS Number: 2169967-47-7
  • Molecular Formula: C36H70O17
  • Molecular Weight: 774.93
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:48:51
  • Modify Date: 2024-01-08 14:34:01
  • Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG17-methane
Description Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C36H70O17
Molecular Weight 774.93