2055024-37-6

2055024-37-6 structure
2055024-37-6 structure
  • Name: Acid-PEG4-Sulfone-PEG4-acid
  • Chemical Name: Sulfone-Bis-PEG4-acid
  • CAS Number: 2055024-37-6
  • Molecular Formula: C22H42O14S
  • Molecular Weight: 562.63
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:49:12
  • Modify Date: 2024-01-02 17:39:49
  • Sulfone-Bis-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Sulfone-Bis-PEG4-acid
Description Sulfone-Bis-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C22H42O14S
Molecular Weight 562.63