1306761-08-9

1306761-08-9 structure
1306761-08-9 structure
  • Name: RP101442
  • Chemical Name: RP101442
  • CAS Number: 1306761-08-9
  • Molecular Formula: C23H22N4O3
  • Molecular Weight: 402.45
  • Catalog: Signaling Pathways GPCR/G Protein LPL Receptor
  • Create Date: 2020-08-07 22:44:16
  • Modify Date: 2024-01-18 17:32:15
  • RP101442, an active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively[1].

Name RP101442
Description RP101442, an active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively[1].
Related Catalog
Target

S1PR1:2.6 nM (EC50)

S1PR5:171 nM (EC50)

References

[1]. Tran JQ, et al. Cardiac Safety of Ozanimod, a Novel Sphingosine-1-Phosphate Receptor Modulator: Results of a Thorough QT/QTc Study. Clin Pharmacol Drug Dev. 2018;7(3):263-276.

Molecular Formula C23H22N4O3
Molecular Weight 402.45