1802078-33-6

1802078-33-6 structure

Name: Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt
Chemical Name: Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt
CAS Number: 1802078-33-6
Molecular Formula: C₈₇H₁₂₉N₂₇O₂₈S
Molecular Weight: 2033.184
Catalog: Research Areas Neurological Disease
Create Date: 2021-01-09 13:13:09
Modify Date: 2024-02-06 14:13:41
Mca-SEVKMDAEFRK(Dnp)RR-NH2, containing the wild-type amyloid precursor protein (APP) beta-secretase cleavage site, is the substrate of thimet oligopeptidase (TOP). It is used for Alzheimer's disease research[1].

Name	Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt
Synonyms	N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-lysyl-L-methionyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-N6-(2,4-dinitrophenyl)-L-lysyl-L- arginyl-L-argininamide L-Argininamide, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-lysyl-L-methionyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-N6-(2,4-di nitrophenyl)-L-lysyl-L-arginyl-

Description	Mca-SEVKMDAEFRK(Dnp)RR-NH2, containing the wild-type amyloid precursor protein (APP) beta-secretase cleavage site, is the substrate of thimet oligopeptidase (TOP). It is used for Alzheimer's disease research[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	others
References	[1]. H Koike, et al. Thimet Oligopeptidase Cleaves the Full-Length Alzheimer Amyloid Precursor Protein at a β-Secretase Cleavage Site in COS Cells. J Biochem. 1999 Jul;126(1):235-42.