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2222280-83-1

2222280-83-1 structure
2222280-83-1 structure
  • Name: SHP504
  • Chemical Name: SHP504
  • CAS Number: 2222280-83-1
  • Molecular Formula: C23H15ClN4O4
  • Molecular Weight: 446.84
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
  • Create Date: 2021-01-08 17:50:42
  • Modify Date: 2024-01-05 13:27:09
  • SHP504 is a SHP2 phosphatase inhibitor, with an IC50 of 21 μM for SHP21–525[1].

Name SHP504
Synonyms 3-(4-(2-chlorobenzyl)-5-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinazolin-1-yl)-4-hydroxybenzoic acid
Description SHP504 is a SHP2 phosphatase inhibitor, with an IC50 of 21 μM for SHP21–525[1].
Related Catalog
References

[1]. Michelle Fodor, et al. Dual Allosteric Inhibition of SHP2 Phosphatase. ACS Chem Biol. 2018 Mar 16;13(3):647-656.

Molecular Formula C23H15ClN4O4
Molecular Weight 446.84
Storage condition 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO