1391052-28-0
1391052-28-0 structure
- Name: PF 4800567 hydrochloride
- Chemical Name: 3-[(3-chlorophenoxy)methyl]-1-tetrahydropyran-4-yl-pyrazolo[3,4-d]pyrimidin-4-amine;hydrochloride
- CAS Number: 1391052-28-0
- Molecular Formula: C17H19Cl2N5O2
- Molecular Weight: 396.271
- Create Date: 2021-01-09 18:19:29
- Modify Date: 2023-01-17 11:44:25
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PF-4800567 hydrochloride is a casein kinase 1e (CK1e) selective inhibitor (IC50 = 32 nM) that is 20 fold selective for the CK1e isoform over CK1d. PF-4800567 blockes CK1e-mediated PER3 nuclear translocation, but does not effect the circadian clock in animal studies.
| Name | 3-[(3-chlorophenoxy)methyl]-1-tetrahydropyran-4-yl-pyrazolo[3,4-d]pyrimidin-4-amine;hydrochloride |
|---|---|
| Synonyms | MFCD20926348 |
| Molecular Formula | C17H19Cl2N5O2 |
|---|---|
| Molecular Weight | 396.271 |
| Exact Mass | 395.091583 |