1398053-45-6
1398053-45-6 structure
- Name: CC 122 HCl
- Chemical Name: Avadomide hydrochloride
- CAS Number: 1398053-45-6
- Molecular Formula: C14H15ClN4O3
- Molecular Weight: 322.747
- Create Date: 2021-01-01 02:17:37
- Modify Date: 2024-01-18 19:55:00
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Avadomide, also known as CC-122, is an orally available pleiotropic pathway modulator with potential antineoplastic activity. CC-122 mimics an interferon response and has antitumor activity in DLBCL CC-122 binds Cereblon (CRBN) and promotes degradation of Aiolos and Ikaros in diffuse large B-cell lymphoma (DLBCL) and T cells in vitro, in vivo, and in patients, resulting in both cell autonomous as well as immunostimulatory effects.
| Name | Avadomide hydrochloride |
|---|---|
| Synonyms |
3-(5-Amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-2,6-piperidinedione hydrochloride (1:1)
Avadomide hydrochloride 2,6-Piperidinedione, 3-(5-amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-, hydrochloride (1:1) CC-122 HCl UNII:28DZS29F59 |
| Molecular Formula | C14H15ClN4O3 |
|---|---|
| Molecular Weight | 322.747 |
| Exact Mass | 322.083282 |