2219324-71-5
2219324-71-5 structure
- Name: BB-Cl-Yne
- Chemical Name: BB-Cl-Yne
- CAS Number: 2219324-71-5
- Molecular Formula: C28H26ClN5O
- Molecular Weight: 483.992
- Create Date: 2021-01-08 07:54:01
- Modify Date: 2024-03-31 16:56:13
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BB-Cl-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-Cl-Yne inhibits PAD1-4 and has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.
| Name | BB-Cl-Yne |
|---|---|
| Synonyms |
N-{(1S)-1-(1H-Benzimidazol-2-yl)-4-[(2-chloroethanimidoyl)amino]butyl}-4'-ethynyl-4-biphenylcarboxamide
[1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-4'-ethynyl- BB-Cl-Yne |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C28H26ClN5O |
| Molecular Weight | 483.992 |
| Exact Mass | 483.182587 |
| LogP | 4.05 |
| Index of Refraction | 1.641 |