Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Aceticacid,2-[3-(2-aminoethoxy)propoxy]-,1,1-dimethylethylester
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Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

1948273-09-3

1948273-09-3 structure

1948273-09-3 structure

Name: tert-Butyl 2-(3-(2-aminoethoxy)propoxy)acetate
Chemical Name: NH2-PEG2-CH2-Boc
CAS Number: 1948273-09-3
Molecular Formula: C₁₁H₂₃NO₄
Molecular Weight: 233.30
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2021-09-13 17:17:53
Modify Date: 2024-01-09 19:42:11
NH2-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	NH2-PEG2-CH2-Boc
Synonyms	MFCD30741911

Description	NH2-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₁H₂₃NO₄
Molecular Weight	233.30