393845-24-4

393845-24-4 structure

Name: 1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
Chemical Name: VU0080241
CAS Number: 393845-24-4
Molecular Formula: C₁₉H₂₃N₅
Molecular Weight: 321.419
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2021-10-05 20:21:25
Modify Date: 2024-01-14 18:06:46
VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM[1].

Name	VU0080241
Synonyms	1-(2,4-Dimethylphenyl)-4-(3-methyl-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine VU0080241 1H-Pyrazolo[3,4-d]pyrimidine, 1-(2,4-dimethylphenyl)-4-(3-methyl-1-piperidinyl)- MFCD03474901

Description	VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGlu4:4.6 μM (EC50)
References	[1]. Colleen M Niswender, et al. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett. 2008 Oct 15; 18(20): 5626-5630.