338965-09-6
338965-09-6 structure
- Name: 5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine
- Chemical Name: 5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine
- CAS Number: 338965-09-6
- Molecular Formula: C16H13Cl2N5
- Molecular Weight: 346.214
- Catalog: Research Areas Metabolic Disease
- Create Date: 2021-09-17 18:38:33
- Modify Date: 2024-09-17 21:44:14
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Hepcidin antagonist-1 (example 104) is a potent hepcidin (hepcidine) antagonist with an IC50<50 μM. Hepcidin antagonist-1 can be used for researching iron metabolism disorders, such as anemias[1].
| Name | 5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine |
|---|---|
| Synonyms |
5-(2,4-Dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine
4,6-Pyrimidinediamine, 5-[(2,4-dichlorophenyl)methyl]-2-(2-pyridinyl)- 5-[(2,4-Dichlorophenyl)methyl]-2-(2-pyridinyl)-4,6-pyrimidinediamine MFCD00231629 |
| Description | Hepcidin antagonist-1 (example 104) is a potent hepcidin (hepcidine) antagonist with an IC50<50 μM. Hepcidin antagonist-1 can be used for researching iron metabolism disorders, such as anemias[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: <50 μM (hepcidin)[1] |
| References |
[1]. Franz DÜRRENBERGER, et al. Novel pyrimidine and triazine hepcidine antagonists. WO2011026835 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 476.1±45.0 °C at 760 mmHg |
| Molecular Formula | C16H13Cl2N5 |
| Molecular Weight | 346.214 |
| Flash Point | 241.8±28.7 °C |
| Exact Mass | 345.054810 |
| LogP | 1.90 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.691 |