32780-32-8

32780-32-8 structure

Name: validamine
Chemical Name: validamine
CAS Number: 32780-32-8
Molecular Formula: C₇H₁₅NO₄
Molecular Weight: 177.20
Catalog: Biochemical Amino acids and their derivatives Other amino acid derivatives
Create Date: 2018-12-25 22:11:36
Modify Date: 2024-01-03 13:26:30
Validamine competitively inhibits β-glucosidase in a pH-dependent and dose-dependent manner, with an IC50 value of 2.92mM, and the maximum inhibitory ability is at the optimum pH value of this enzyme[1].

Name	validamine
Synonyms	PT 141 Pt141 Acetate (1R,2S,3S,4S,6R)-4-Amino-6-(hydroxymethyl)-1,2,3-cyclohexanetriol 1s-(1,2,4/3,5)-1-amino-5-hydroxymethyl-2,3,4-cyclohexantriol 1,2,3-Cyclohexanetriol, 4-amino-6-(hydroxymethyl)-, (1R,2S,3S,4S,6R)- MFCD08063357 (1R,2S,3S,4S,6R)-4-Amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol Bremelanotide Acetate Validamine 1-Amino-5-(hydroxymethyl)-1,5,6-trideoxy-D-chiro-inositol (1R,2S,3S,4S)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol PT-141 (BREMELANOTIDE) Bremelanotide,PT141,Acetate 1-Amino-1,5,6-trideoxy-5-(hydroxymethyl)-D-chiro-inositol

Description	Validamine competitively inhibits β-glucosidase in a pH-dependent and dose-dependent manner, with an IC50 value of 2.92mM, and the maximum inhibitory ability is at the optimum pH value of this enzyme[1].
Related Catalog	Research Areas >> Metabolic Disease
Target	IC50 value of 2.92mM[1]
References	[1]. Takeuchi M, et al. Inhibitory effect of validamine, valienamine and valiolamine on activities of carbohydrases in rat small intestinal brush border membranes. Chem Pharm Bull (Tokyo). 1990 Jul;38(7):1970-2.

HS Code	2922199090

HS Code	2922199090
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%