32695-27-5

32695-27-5 structure
32695-27-5 structure
  • Name: Dapsone hydroxylamine
  • Chemical Name: Dapsone Hydroxylamine
  • CAS Number: 32695-27-5
  • Molecular Formula: C12H12N2O3S
  • Molecular Weight: 264.30000
  • Catalog: Chemical reagent Organic reagent Sulfone, sulfoxide compound
  • Create Date: 2018-06-20 17:39:34
  • Modify Date: 2024-01-21 05:54:46
  • Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity[1].

Name Dapsone Hydroxylamine
Synonyms N-[4-(4-aminophenyl)sulfonylphenyl]hydroxylamine
Description Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity[1].
Related Catalog
References

[1]. Albuquerque RV, et al. In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells. PLoS One. 2015 Aug 18;10(8):e0134768.  

[2]. Wozel G, et al. Dapsone hydroxylamine inhibits the LTB4-induced chemotaxis of polymorphonuclear leukocytes into human skin: results of a pilot study. Inflamm Res. 1997 Oct;46(10):420-2.  

Density 1.464g/cm3
Boiling Point 531.1ºC at 760mmHg
Melting Point 194ºC dec.
Molecular Formula C12H12N2O3S
Molecular Weight 264.30000
Flash Point 275ºC
Exact Mass 264.05700
PSA 100.80000
LogP 3.63770
Index of Refraction 1.69
Storage condition Amber Vial, -20°C Freezer
Stability Light Sensitive, Temperature Sensitive
HS Code 2922199090

~80%

32695-27-5 structure

32695-27-5

Literature: Vyas, Piyush M.; Roychowdhury, Sanjoy; Woster, Patrick M.; Svensson, Craig K. Biochemical Pharmacology, 2005 , vol. 70, # 2 p. 275 - 286

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32695-27-5 structure

32695-27-5

Literature: Clinical Pharmacology and Therapeutics, , vol. 58, # 5 p. 556 - 566
Precursor  2

DownStream  1

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%