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788824-64-6

788824-64-6 structure
788824-64-6 structure
  • Name: 4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride
  • Chemical Name: 4-[4-(2-aminoethyl)-2-iodophenoxy]phenol,hydrochloride
  • CAS Number: 788824-64-6
  • Molecular Formula: C14H15ClINO2
  • Molecular Weight: 391.63
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2017-07-08 10:42:47
  • Modify Date: 2024-01-29 16:18:42
  • 3-Iodothyronamine (hydrochloride) is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure[1].

Name 4-[4-(2-aminoethyl)-2-iodophenoxy]phenol,hydrochloride
Synonyms Phenol,4-[4-(2-aminoethyl)-2-iodophenoxy]-,hydrochloride
2-[4-(4-Hydroxyphenoxy)-3-iodophenyl]ethanaminium chloride
4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride
3-Iodothyronamine Hydrochloride
Phenol, 4-[4-(2-aminoethyl)-2-iodophenoxy]-, hydrochloride (1:1)
Description 3-Iodothyronamine (hydrochloride) is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure[1].
Related Catalog
References

[1]. Hart ME, et al. Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues. J Med Chem. 2006 Feb 9;49(3):1101-12.  

Melting Point 209-211ºC
Molecular Formula C14H15ClINO2
Molecular Weight 391.63
Exact Mass 390.983582
PSA 55.48000
LogP 4.79260
Hazard Codes C