1035373-85-3

1035373-85-3 structure

Name: 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride
Chemical Name: 2-[2-(6-chloro-hexyloxy)-ethoxy]-ethylamine hydrochloride
CAS Number: 1035373-85-3
Molecular Formula: C₁₀H₂₃Cl₂NO₂
Molecular Weight: 260.20112
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2021-11-16 11:07:56
Modify Date: 2024-01-14 16:11:16
2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-(6-chloro-hexyloxy)-ethoxy]-ethylamine hydrochloride
Synonyms	2-{2-[(6-Chlorohexyl)oxy]ethoxy}ethanamine hydrochloride (1:1) Ethanamine, 2-[2-[(6-chlorohexyl)oxy]ethoxy]-, hydrochloride (1:1)

Description	2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Hazard Codes	Xi