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  • DC Chemicals Limited
  • China
  • Product Name: Mongersen
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1443994-46-4

1443994-46-4 structure
1443994-46-4 structure
  • Name: Mongersen
  • Chemical Name: Mongersen
  • CAS Number: 1443994-46-4
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Signaling Pathways Stem Cell/Wnt TGF-beta/Smad
  • Create Date: 2022-04-07 20:31:29
  • Modify Date: 2024-01-11 19:38:24
  • Mongersen is a 21-mer phosphorothioate antisense oligonucleotide targeting the mRNA of the Smad7 protein, thus leading to suppression of TGF-β1 pathways and remission of Crohn's disease.

Name Mongersen
Description Mongersen is a 21-mer phosphorothioate antisense oligonucleotide targeting the mRNA of the Smad7 protein, thus leading to suppression of TGF-β1 pathways and remission of Crohn's disease.
Related Catalog
References

[1]. Monteleone G, Neurath MF, Ardizzone S, et al. Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease. N Engl J Med. 2015;372(12):1104-1113.

No Any Chemical & Physical Properties