2477608-96-9

2477608-96-9 structure

Name: Antileishmanial agent-8
Chemical Name: Antileishmanial agent-8
CAS Number: 2477608-96-9
Molecular Formula: C₁₈H₁₆O₄
Molecular Weight: 296.32
Catalog: Research Areas Infection
Create Date: 2022-07-01 17:17:41
Modify Date: 2024-04-06 10:50:45
Antileishmanial agent-8 (compound 18) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 5.64 μM. Antileishmanial agent-8 has relatively low cytotoxicity in L-6 cells (IC50=73.9 μM)[1].

Name	Antileishmanial agent-8

Description	Antileishmanial agent-8 (compound 18) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 5.64 μM. Antileishmanial agent-8 has relatively low cytotoxicity in L-6 cells (IC50=73.9 μM)[1].
Related Catalog	Research Areas >> Infection
Target	IC50: 5.64 μmol/L (L. donovani)[1]
References	[1]. Bernal FA, et al. (±)-trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem. 2020;205:112493.

Molecular Formula	C₁₈H₁₆O₄
Molecular Weight	296.32