1214454-56-4

1214454-56-4 structure

Name: Antimalarial agent 11
Chemical Name: Antimalarial agent 11
CAS Number: 1214454-56-4
Molecular Formula: C₂₅H₂₅F₂NO₃
Molecular Weight: 425.47
Catalog: Research Areas Infection
Create Date: 2022-07-01 16:28:19
Modify Date: 2024-04-06 17:42:59
Antimalarial agent 11 (compound 1), a spirocyclic chromane, is a potent antimalarial agent. Antimalarial agent 11 exhibits excellent potency with an EC50 of 350 nM against the Chloroquine-resistant Dd2 strain. Antimalarial agent 11 has EC50s of 1.48 µM and 1.81 µM against D6 and ARC08-022 strains, respectively[1].

Name	Antimalarial agent 11

Description	Antimalarial agent 11 (compound 1), a spirocyclic chromane, is a potent antimalarial agent. Antimalarial agent 11 exhibits excellent potency with an EC50 of 350 nM against the Chloroquine-resistant Dd2 strain. Antimalarial agent 11 has EC50s of 1.48 µM and 1.81 µM against D6 and ARC08-022 strains, respectively[1].
Related Catalog	Research Areas >> Infection
References	[1]. Iredia D Iyamu, et al. Structure-activity and structure-property relationship studies of spirocyclic chromanes with antimalarial activity. Bioorg Med Chem. 2022 Mar 1;57:116629.

Molecular Formula	C₂₅H₂₅F₂NO₃
Molecular Weight	425.47