2494277-80-2

2494277-80-2 structure

Name: Antiparasitic agent-2
Chemical Name: Antiparasitic agent-2
CAS Number: 2494277-80-2
Molecular Formula: C₂₀H₁₇N₃O₃
Molecular Weight: 347.37
Catalog: Research Areas Infection
Create Date: 2022-07-11 14:30:23
Modify Date: 2024-04-06 17:17:48
Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM)[1].

Name	Antiparasitic agent-2

Description	Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM)[1].
Related Catalog	Research Areas >> Infection
Target	IC50: 7.28 μM (L. infantum), 2.30 μM (T. cruzi)[1]
References	[1]. Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.

Molecular Formula	C₂₀H₁₇N₃O₃
Molecular Weight	347.37