2497686-66-3

2497686-66-3 structure

Name: RMS3
Chemical Name: RMS3
CAS Number: 2497686-66-3
Molecular Formula: C₃₈H₃₉F₃N₂O₆
Molecular Weight: 676.72
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-08-18 18:32:35
Modify Date: 2024-04-07 08:39:41
RMS3, a tetrandrine analogue, is a potent P-glycoprotein (P-gp) inhibitor. RMS3 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS3 has strong anticancer property[1].

Name	RMS3

Description	RMS3, a tetrandrine analogue, is a potent P-glycoprotein (P-gp) inhibitor. RMS3 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS3 has strong anticancer property[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein
References	[1]. RamonaSchütz, et al. Synthesis, biological evaluation and toxicity of novel tetrandrine analogues. Eur J Med Chem. 2020 Dec 1;207:112810.

Molecular Formula	C₃₈H₃₉F₃N₂O₆
Molecular Weight	676.72